Hero Passive - Perk Interactions

Two of the most common questions players ask is “Which hero is better?” and “Which perks to take?”

Having a go at answering this requires (among other things) an understanding of how Hero Skills interact with Perks:

Hero Skill Advantaged Perks Disadvantaged Perks
Mr. Autofire None None None
Dr. Toxic Venom Shots None None
Frostina Snowball Piercing and Bouncy Walls make a big impact, which is why starting with the Looper / Laser Rifle is very useful.
For endless runs it might be OK to lose a perk roll to get Piercing (it’s a very common perk so you will almost certainly get it) and Ghost + Dimensional shots might be an alternative to Bouncy (but Ghost itself is uncommon and Dimensional is as rare as Super Homing / Dividing, so you won’t get this often)
Shrapnel and elemental perks (Ice, Zap, Fire, Poison (*2)) do not benefit from Snowball
Blazia Wrath Focus Shots Shrapnel and elemental perks (Ice, Zap, Fire, Poison(*2)) do not benefit from Wrath
Arctor Freeze Speed perks and Indirect hits will help Freeze enemies faster None
Scorcher Stress Shot Shrapnel (except Death), Ice/Improved Ice, Zap If you are able to play him for his Passive (i.e. at reduced health), Speed perks are slightly less impactful because they add to the passive (so while generally Attack Speed > Attack Up, for him it might be the opposite)
Miasma Absorb None None
Armorita Gravity Well None None
Firebug Fiery Wings Triple Jump, Jet Pack, Springs and Balloon will increase the up-time of Fiery Wings;
Shrapnel (except Death), Ice/Improved Ice, Zap will occur more often
Speed perks are slightly less impactful because they add to the passive (so while generally Attack Speed > Attack Up, for her it might be the opposite)
Fiery Wings won’t trigger when using Ninja
Time Stop and Sustained Fire don’t work if you are jumping for speed, but are handy as insurance for when you need to stay still
Fursus Iceplosion Speed perks, Shrapnel and Indirect hits (*1) None of the Attack perks (Big Attack Up, Gun Heart, Fast Shots, Power Tripper, Berserk) increase the Iceplosion damage
Hocus Focus Clairvoyance None None
Hecate Magic Bubble None None of the Attack perks (Big Attack Up, Gun Heart, Fast Shots, Power Tripper, Berserk) increase the Magic Bubble damage
Jackbot Jackpot Speed perks, Shrapnel and Indirect hits (*1) Many - see the Jackbot listing
Mortis Plague Cloud Speed perks, Shrapnel and Indirect hits (*1) None of the Attack perks (Big Attack Up, Gun Heart, Fast Shots, Power Tripper, Berserk) increase the Plague Cloud damage and perhaps the already useless Poison may be a little less useful now that the Plague Cloud also poisons enemies
Prospero Magic Bullets Elemental Perks (Ice, Fire, Poison, Zap) because Magic Bullets trigger them
Berserk doesn’t improve Magic Bullets damage (whereas other Attack perks - Big Attack Up, Gun Heart, Fast Shots and Power Tripper - do)
Mrs. Surefire Crowd Control Shrapnel (except Death), Ice/Improved Ice, Zap Speed perks are slightly less impactful because they add to the passive (so while generally attack speed > attack up, for her it might be the opposite)
Shiver Cryo Shield None None

Note:

*1 All of these are hit based proc’s, and are more likely to trigger when having more hits/second

*2 - Fire and Poison are generally undesirable perks - they don’t do much damage and they pollute the perk pool with their “improved” versions


See also:
Hero Passive - Weapon Interactions
Weapon - Perk interactions